NOT KNOWN FACTUAL STATEMENTS ABOUT NR1-SITE

Working with this technique, Kalbaugh et al. assigned affinity and efficacy roles to positions in the LBDs on the NR1 and NR2A NMDAR subunits. In situ mutation of residues in immediate connection with sure ligand affected equally efficacy and affinity, although positions that stabilize the closed cleft conformation with no direct ligand conversatio